1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).
2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.
3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.
Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:
Top Drug-Drug Interactions
interactionsWhile looking for drug-food interactions, be sure to "&" and not look at "." You can alsoraints
Tadalafil is a medication used to treat erectile dysfunction (ED). It works by increasing blood flow to the penis, resulting in improved erectile function. This mechanism allows for improved sexual performance and intimacy with the partner. Tadalafil is available in the form of tablets and is taken orally, usually at least 30 minutes before anticipated sexual activity. The recommended starting dose is 50 mg, taken once a day, but it may be increased to a maximum of 100 mg or decreased to 25 mg depending on the severity of the condition. Dosages are determined by the doctor based on individual response and tolerance, but are generally not greater than 200 mg. Tadalafil is often taken with or without food, but can be taken up to 6 hours before sexual activity. It is important to follow the doctor's instructions carefully, especially if you have underlying health conditions or are taking other medications.
While it is generally safe to drink alcohol with tadalafil, it can cause side effects such as dizziness, headache, and nausea. The most common side effects of tadalafil include increased heart rate, headache, and dizziness. It is important to talk to your doctor before taking tadalafil to ensure safe and effective use.
Tadalafil is a prescription medication that is used to treat erectile dysfunction (ED). Tadalafil is available in the form of tablets and is taken orally, usually at least 30 minutes before sexual activity. Tadalafil is taken orally, usually at least 30 minutes before sexual activity. Common side effects of tadalafil include increased heart rate, headache, and dizziness.
Tadalafil is a prescription medication used to treat erectile dysfunction (ED). Tadalafil should be taken with or without food, but can be taken up to 6 hours before sexual activity. It is important to take tadalafil at the same time each day to maintain its effectiveness.
Before we explain how Tadalafil helps manage ED, we need to explain how erections occur naturally. When you become aroused, your body releases a substance called nitric oxide (NO). In turn, levels of a chemical known as cyclic guanosine monophosphate (cGMP) increase in your body, relaxing the muscles on the sides of your penis so blood can flow into the organ and trigger a stiff erection.
While all this is happening, your body also compresses the veins that take blood away from the penis, so that the blood remains in place and you can maintain that erection. Eventually, the PDE5 enzyme in your body gets to work, and it processes the cGMP. When that happens, your erection dissipates, and the penis becomes flaccid once again.
If you have ED, regardless of the underlying cause, this natural process is somehow interrupted. That makes it more difficult for you to get or maintain an erection that’s sufficient for intercourse. And that’s where Tadalafil, a PDE5 inhibitor, can help. By blocking this enzyme in your body, you’ll have an easier time getting an erection and holding on to it until sex is complete.
As we mentioned earlier, erections that persist for about four hours are enough to get you through sex.
If you think you’re having an ED, seek immediate medical attention and contact a doctor or pharmacist for assistance. Even if you don’t have ED, a doctor will do lab tests (such as PDE5 inhibitors) to check for signs of cGMP elevation in the penis, to prevent a weak erection that doesn’t meet expectations with sex.
Tadalafil is a proven and well-tolerated oral medication that treats ED. It works by relaxing the blood vessels in the penis, allowing more blood to flow into it when you get sexually excited.
It’s important to note that tadalafil is not a cure for ED. And if you’re experiencing ED, there’s going to be a bit of a delay in treatment in deciding to get help for it until that treatment is finished, so long as you don’t experience ED with other medications that treat ED.
When you have ED, you’re definitely not going to just relax and take a deep breath. When you’re aroused, your body releases nitric oxide (NO), which activates the enzyme guanylate cyclase (GC). That causes the nerve cells that line the organ to turn over faster.
If you’re prescribed tadalafil and have been told that you’re having an ED, you don’t have to wait too much longer to get help. Most of the time it’s a fast-acting solution that stays effective for about four hours.
If you’re experiencing severe or persistent side effects, you should speak to a doctor or pharmacist first. That’s because a potential side effect that may be experienced is an allergic reaction. If it happens too soon (such as without a rise in red blood cells), get medical help and let’s discuss the possibility of a serious allergic reaction.
As you can tell by your doctor’s visit, tadalafil can cause liver damage in some individuals. And that’s because tadalafil can affect the liver. That means that you’ll get more side effects when you take tadalafil.
That’s because liver damage can occur with tadalafil, especially if you’re older, have a history of liver disease or are taking medications that can cause a low level of liver function in the elderly.
It’s important to keep in mind that tadalafil can cause liver damage even if you’re allergic to it. In fact, more than half of the 1.2 million US adults are not able to get or keep an erection that’s adequate for sex.
And that’s because the FDA has been monitoring tadalafil levels in the body for almost a year and a half. And they’re seeing a dramatic increase in side effects.
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ContraindicationsHealthylife has a history of allergy to tadalafil or any of the ingredients in this product. Symptoms of an allergic reaction may include: rash, itching, hives, and trouble breathing.
Warnings or restrictions Do not use this product within 6 months of sexual activity because the effectiveness may be affected. If you are not sure if you are using this product, discuss with your healthcare professional before use, as they may be able to help identify the reason for your intolerance to some medications. Additionally, this product does not help with impotence. Do not use this product if you are allergic to any of the ingredients in this product. If you are using tadalafil 20mg tablet, then you should read the label carefully and ask your healthcare professional if you have to use this product. Also, this product does not affect the kidney or liver function in patients with kidney problems. This product should not be used to treat impotence. If you have any questions about this product, contact the healthcare professional.Ask your pharmacist or doctor before use if you are allergic to any of the following:Healthylife has tested all of these ingredients well and has not found any adverse reactions to them. If you have concerns about the contents of this email message, please read the labels on your chosen product packaging. It is important for patients to read the label and follow the directions for use. If you are using tadalafil 20mg tablet, read the label carefully and ask your healthcare professional if you have questions about this product. Also, this product should not be used to treat impotence. If you are using tadalafil 20mg tablet, inform your healthcare professional before use, as they may be able to help identify the reason for your intolerance to some medications. Do not use this product if you are using tadalafil 20mg tablet, as it may worsen the condition. Additionally, this product should not be used to treat impotence.
Support and advertise this product: If you are a health professional and would like to talk to our pharmacist about signing up, please contact [email protected].1. KD. Tripathi. Androgens and Drugs for Erectile Dysfunction. Essentials of medical pharmacology. Seventh edition. 2013. Page-304.
2. Adam M Henrie, James J Nawarskas, and Joe R Anderson. Clinical utility of tadalafil in the treatment of pulmonary arterial hypertension: an evidence-based review. NIH. National Library of Medicine. National Center for Biotechnology Information. PMC. PubMed Central. November 2015. [Accessed on November 08th, 2023]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4636095/
3. Accord Healthcare Limited. Electronic Medicines Compendium (EMC). [Revised in October 2021] [Accessed on November 08th, 2023]https://www.medicines.org.uk/emc/files/pil.8637.pdf
4. Leeford Healthcare Private Ltd. Bigfun-36.https://www.leeford.in/product/556/bigfun-36
5. Central Drugs Standard Control Organization. Tadalafil tablet 20 mg (Additional Indication). [Revised in November 2009]. Tadalafil 10mg/20mg Tablets. [Revised in September 2003] [Accessed on November 08th, 2023]https://cdscoonline.gov.in/CDSCO/Drugs
Tadalafil (CADO. T20-C14) ECDOUE. [Revised in June 2015] [Accessed on November 08th, 2023]https://www.ncbi.nlm.nra. View/CADOPulmonary Arterial Hypertension. Mechanism of Action: Pharmacodynamics and Efficacy: A Viatris Guide. pd1001HT12. [Revised in September 2019] [Accessed on November 08th, 2023]